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In this talk, Andrew Gaffney is joined by Stephen Sullivan from the Global Alliance for iPSC Therapies (GAiT) to discuss the importance of iPSC characterization as well as risks and mitigation strategies involved in creating a cell therapy.

This webinar describes steps and considerations involved in translating research to the clinic.

In this talk, Drs. Sandra Petrus-Reurer and Álvaro Plaza Reyes share their research on using human pluripotent stem cell (hPSC)-derived retinal epithelial cells (RPE) to treat age-related macular degeneration (AMD) and describe the steps and hurdles associated with bringing an hPSC-derived product to the clinic. This seminar is followed by a presentation from Lynn Csontos, in-house quality expert from ���ϳԹ�, who discusses compliance considerations for clinical-grade induced pluripotent stem cells.

Dr. Peter Coffey from University College London shares his work with the London Project to Cure Blindness, which resulted in the first clinical stem cell trial to treat blindness, and discusses cell quality requirements for clinical trials. This presentation and the following Q&A session were moderated by Dr. Christine Mummery from the Leiden University Medical Center. <br><br> This presentation was part of a Round Table series titled “Challenges in Ensuring hPSC Quality”, hosted in partnership with Nature Research. Global experts gathered at the Springer Nature headquarters in London, UK, to tackle some of the most pertinent issues impacting the use of human pluripotent stem cells (hPSCs), ranging from fundamental biology research to therapeutic applications. Explore the full series <a href="/nature-research-roundtable-hPSC-quality#section-webcasts">here</a>. <br><br> Note: Some original data from this presentation has been omitted to abide by copyright rules.

Dr. Malin Parmar from Lund University talks about her work on cell-based therapies to treat Parkinson’s disease, as well as regulatory, safety, and efficacy requirements for the clinic. This presentation and the following Q&A session were moderated by Dr. Christine Mummery from the Leiden University Medical Center. <br><br> This presentation was part of a Round Table series titled “<a href="/nature-research-roundtable-hPSC-quality#section-webcasts">Challenges in Ensuring hPSC Quality</a>”, hosted in partnership with Nature Research. Global experts gathered at the Springer Nature headquarters in London, UK, to tackle some of the most pertinent issues impacting the use of human pluripotent stem cells (hPSCs), ranging from fundamental biology research to therapeutic applications. Explore the full series <a href="/nature-research-roundtable-hPSC-quality#section-webcasts">here</a>. <br><br> Note: Some original data from this presentation has been omitted to abide by copyright rules.

In this panel discussion led by Dr. Christine Mummery from the Leiden University Medical Center, keynote speakers respond to questions from the forum and evaluate consensuses around topics raised in the previous talks. <br><br> This panel discussion was part of a Round Table series titled “<a href="/nature-research-roundtable-hPSC-quality#section-webcasts">Challenges in Ensuring hPSC Quality</a>”, hosted in partnership with Nature Research. Global experts gathered at the Springer Nature headquarters in London, UK, to tackle some of the most pertinent issues impacting the use of human pluripotent stem cells (hPSCs), ranging from fundamental biology research to therapeutic applications. Explore the full series <a href="/nature-research-roundtable-hPSC-quality#section-webcasts">here</a>.

Dr. Glyn Stacey, Director of the International Stem Cell Banking Initiative (ISCBI), discusses standards for pluripotent stem cell (PSC) banking with a focus on scientific challenges for PSCs, standardization of ethics, the role of stem cell biobanks, and best practices for cell therapy. This presentation and the following Q&A session were moderated by Dr. Joanne Mountford from the University of Glasgow. <br><br> This presentation was part of a Round Table series titled “<a href="/nature-research-roundtable-hPSC-quality#section-webcasts">Challenges in Ensuring hPSC Quality</a>”, hosted in partnership with Nature Research. Global experts gathered at the Springer Nature headquarters in London, UK, to tackle some of the most pertinent issues impacting the use of human pluripotent stem cells (hPSCs), ranging from fundamental biology research to therapeutic applications. Explore the full series <a href="/nature-research-roundtable-hPSC-quality#section-webcasts">here</a>.

Analyze genomic DNA samples using the Human Pluripotent Stem Cell (hPSC) Genetic Analysis Kit