Inflammatory and Autoimmune Diseases
Inflammatory and autoimmune diseases are often caused by genetic and environmental factors that give rise to aberrant immune responses. Controlling host immune responses without eliminating the ability to control infections is crucial to managing these diseases.
Below is a collection of scientific resources for your inflammatory and autoimmune disease research.
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Frequencies of Cell Types in Human Peripheral Blood
This wallchart provides a list of the frequencies of cell types in human peripheral blood, as well as the column-free cell isolation kits available for each cell type.
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Cell Isolation Directly from Whole Blood without RBC Lysis or Centrifugation: EasySep™ DirectIntroduction to the EasySep™ Direct immunomagnetic cell separation platform -
Reducing Platelet Contamination in Blood SamplesPlatelets (thrombocytes), cell fragments derived from megakaryocytes, are used in normal blood clotting, and must be handled gently to prevent activation -
Using EasySep™ Positive Selection Kits for Cell DepletionThe EasySep™ system allows you to use a positive selection kit to deplete the labeled cell type, by making changes to the separation scheme of the protocol -
Using Cell Density Gradients to Optimize Your Cell IsolationsRosetteSep™, a unique immunodensity cell isolation platform, isolates highly purified cells by density gradient centrifugation without columns or magnets -
How EasySep™ Magnetic Cell Separation Technology Works: Fast and Easy Cell IsolationEasySep™ technology, a fast and easy immunomagnetic cell separation technology that allows you to isolate virtually any cell types from a variety of sample sources in as little as 8 minutes -
How to Isolate Nucleated Cells from Whole Blood Using HetaSep™ Erythrocyte Aggregation AgentHetaSep™ is an erythrocyte aggregation agent used to quickly separate nucleated cells from red blood cells -
How to Isolate Cells Directly from Whole Blood Using the EasySep™ Purple/Silver MagnetsHow to isolate highly purified immune cells directly from whole blood and takes as little as 20 minutes from start to finish -
Modeling Alzheimer's risk using human TREM2-knockout microgliaAmanda McQuade from Dr. Mathew Blurton-Jones’s lab discusses her protocol for differentiating microglia from induced pluripotent stem cells (iPSCs) and the use of these microglia in vivo and in vitro to uncover the mechanisms of immune activation and neurodegeneration in Alzheimer’s disease. -
Processing Multiple Samples at One Time with the EasyEights™ MagnetThe EasyEights™ EasySep™ Magnet is for cell separation procedures using selected EasySep™ reagents when simultaneously processing multiple samples -
How to Isolate Cells with EasySep™ Column-Free Cell Separation TechnologyIsolation of human CD4+ T cells by negative selection using EasySep™ to separate highly purified cells in as little as 8 minutes -
How to Isolate PBMCs from Whole Blood Using the SepMate™ PBMC Isolation Tubes: 15-Minute ProtocolEasy and rapid procedure for isolating peripheral blood mononuclear cells (PBMCs) from whole blood or bone marrow using the unique SepMate™ PBMC isolation tubes -
Acquiring DNA or RNA from Positively Selected CellsCells positvely selected with the EasySep™ system do not interfere with most downstream applications
