Mammary Research
The mammary gland is a dynamic organ that undergoes extensive morphological changes through development, puberty, pregnancy, lactation and involution. Maintenance of the mammary epithelium during all of these stages is via mammary stem/progenitor cells.
Below is a collection of resources to support your mammary research.
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Mammary Stem Cells and Breast Cancer
This mini-review describes the organization of mammary epithelium, identification of mammary stem and progenitor cells, phenotypic profiling and cell culture methods for mammary epithelial cells, as well as the current understanding of mammary stem cells in the context of breast cancer.
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Mammary Stem Cells and Breast CancerThe mammary gland is composed of a series of branched epithelial ducts that drain alveolar structures during lactation, with the epithelium embedded within a fibrous and fatty stroma -
Optimization of ALDEFLUOR™ Assay for Detection of ALDH Activity in Your Cell Type of InterestALDEFLUOR™ reagent system is a non-immunological method to identify human stem and progenitor cells based on their aldehyde dehydrogenase (ALDH) activity -
Optimization of ALDEFLUOR™ ProtocolLearn how ϳԹ' scientists doubled the signal strength in mammary epithelial cells with a few simple protocol modifications using ALDEFLUOR™ to detect Aldehyde Dehydrogenase bright (ALDHbr) cells -
How ALDEFLUOR™ ALDH Assay Kit Detects Normal and Cancer Progenitor CellsHow the ALDEFLUOR™ assay works to detect aldehyde dehydrogenase (ALDH)-bright cells -
SnapShot: Breast CancerOverview of signaling pathways, commonly mutated genes and breast cancer subtypes -
Small Molecules, Big Impact in Cancer ResearchOverview of signaling pathways and small molecules in cancer research -
Bright Ideas Podcast: ALDH in Breast Cancer Treatment ResponseTune in to this 10-minute Bright Ideas With ALDEFLUOR™ podcast to learn about a recent publication that demonstrated a key role for ALDH in breast cancer treatment response
