Reprogramming of Pluripotent Stem Cells
Human induced pluripotent stem (hiPS) cells are generated by reprogramming somatic cells to a pluripotent state, through the transient overexpression of key reprogramming factors.
Explore the resources below for information on the reprogramming of hPSCs.
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ReproRNA™-OKSGM: Reprogramming Vector for Human iPS Cell Generation
This technical video demonstrates how to reprogram fibroblasts in ReproTeSR™ medium using ReproRNA™-OKSGM. ReproRNA™-OKSGM is a non-integrating, self-replicating RNA reprogramming vector for generating human induced pluripotent (iPS) cells.
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iPSCs As Models, Part 1: What Are Induced Pluripotent Stem Cells and How Do You Use Them?Hear from Dr. Anjana Nityanandam, Director of the Human Stem Cell Lab core facility at St. Jude Children’s Research Hospital, as she provides some introductory examples of how iPSCs are used for disease modeling and walks through how to generate and characterize iPSCs. Learn about quality control measures to improve reliability and reproducibility of data, and how to address interline variability in your experiments. -
Tips for Reprogramming Somatic Cells using TeSR™-E7™Tips to help resolve 2 common issues encountered when reprogramming fibroblasts using TeSR™-E7™ -
Small Molecules, Big Impact in Pluripotent Stem Cell ResearchOverview of signaling pathways and small molecules in pluripotent stem cell research -
Pluripotent Stem Cell BiologyNuclear transfer, reprogramming and cell fusion to induce pluripotency in somatic cells
