T Cell Therapy
Adoptive T cell therapy has brought excitement to immuno-oncology research and hope to cancer patients who are out of treatment options. The most popular form of T cell for therapy are chimeric antigen receptor (CAR) T cells. These cells are engineered to express a synthetic transmembrane receptors containing the variable domain of an antibody to redirect their specificity to recognize and eliminate cancer cells upon infusion in patients.
Below is a collection of scientific resources for your T cell therapy research.
Rational Combination of Cancer Therapies with PD1 Axis Blockade
This free wallchart from Nature Reviews Cancer and Nature Reviews Immunology provides a detailed overview of cancer-immune pathways, combination immunotherapies, and more.
Get Your Free Copy >- Tools for Optimizing Human Immune Cell ResearchObtaining consistent and reliable results when culturing immune cells can be challenging. Watch this webinar to discover how to obtain high yields of functional T cells, NK cells, B cells, dendritic cells, and macrophages for your research applications. The speaker, Evan Karas, also explains how to expand primary T cells without feeders or serum.
- Accelerating T Cell Therapy ResearchObtaining high yields of viable engineered T cells for cell therapy research and immunotherapy development can be challenging. Lengthy and inefficient processes for cell isolation, cell culture, and gene transfer can cause delays and prevent scientists from reaching their goals. Watch as Drs. Sneha Balani and Angela Zhang discuss best practices and innovative technologies for T cell therapy research.
- Lost in Translation - Moving Your Research to Clinical TrialsThis webinar describes steps and considerations involved in translating research to the clinic.
- Optimized Workflows for High-Efficiency Genome Editing in Stem and Primary Cell TypesCRISPR-Cas genome editing in cell culture systems is a powerful technique for disease modeling and the development of cellular therapies. Compared to work with immortalized cell lines, genome editing of stem and primary cells presents unique challenges, including issues related to efficient delivery and expression of CRISPR machinery, clonogenicity, and cytotoxicity. In this webinar, our in-house expert, Dr. Ashley Watson, discusses optimized workflows for CRISPR-Cas9 genome editing in human pluripotent stem cells and primary T cells.
- CAR T Cell Manufacturing Workflow: Isolation, Activation and ExpansionLearn about human T cell isolation, activation, and expansion workflow for cell therapy
- How EasySep™ Magnetic Cell Separation Technology Works: Fast and Easy Cell IsolationEasySep™ technology, a fast and easy immunomagnetic cell separation technology that allows you to isolate virtually any cell types from a variety of sample sources in as little as 8 minutes
- How to Isolate Cells with EasySep™ Column-Free Cell Separation TechnologyIsolation of human CD4+ T cells by negative selection using EasySep™ to separate highly purified cells in as little as 8 minutes